Category: Personalized Medicine

  • By Kevin E. Noonan — The promise of an era of "personalized medicine" has been pursued for a generation, being one of the rationales for and purported benefits of the Human Genome Project.  It has become such a sought-for goal that it has been used to drive policy:  it is something that health care reform…

  • By Kevin E. Noonan — A decade after completion of the Human Genome Project, and after more than a decade of hyperbole regarding the promise and benefits of "personalized medicine," genetic diagnostic testing has come to the attention of Congress.  For example, Representative Debbie Wasserman Schultz (D-FL) introduced a provision of the Leahy-Smith America Invents…

  • By Andrew Williams — On June 29, a panel at the 2011 BIO International Conference discussed the topic of "IP Challenges for Personalized Medicine: Navigating Bilski, Myriad, and Prometheus."  This session addressed one of the most prevalent issues at this year's conference — are the courts going to alter the intellectual property landscape for biomarkers…

  •     By Kevin E. Noonan — Early last week, the Journal of the American Medical Association published a study ("Interaction Between the Serotonin Transporter Gene (5-HTTLPR), Stressful Life Events, and Risk of Depression") by Neil Risch at the University of California, San Francisco and colleagues at the National Institutes of Mental Health, Johns Hopkins University,…

  •     By Kevin E. Noonan — Sickle cell anemia was the first known human disease associated with a genetic polymorphism (an A→T single nucleotide polymorphism, or SNP), resulting in the substitution of a valine residue (encoded by a GTG codon) for a glutamic acid residue (encoded by a GAG codon) in the beta chain of…